More sedating antidepressants for insomnia
Most antidepressants relieve depression by affecting these neurotransmitters. The higher the dose, the more marked are the effects. The extremely limited nature of this evidence and the small scale of most of these studies strongly argues against the use of antidepressants as hypnotics in non-depressed patients.
No other trazodone studies have been reported in primary insomnia patients. Both of these studies evaluated single-dose interactions in healthy volunteers. Insomnia comorbid with depression may be treated using a single hypnotic, a single antidepressant, a combination of two antidepressants, and a combination of one antidepressant and one hypnotic. How a medication worked for a first-degree relative, such as a parent or sibling, can indicate how well it might work for you.
Treatment issues related to sleep and depression. Trazodone for antidepressant-associated insomnia.
These medications don't fit neatly into any of the other antidepressant categories. Nordic Antidepressant Study Group.
Sleep efficiency, sleep latency, and wake time appeared to be unaffected by active treatment. The downside of many sedating antidepressants is that they have side effects at the high doses typically prescribed for people with depression. Side effects included dry mouth and the anticholinergic properties of the drug.
Mendlewicz J, Lecrubier Y. Many antidepressants cause side effects that improve with time. Place of chronic insomnia in the course of depressive and anxiety disorders. Its use is limited, however, because it can cause considerable weight gain.
So tricyclic antidepressants generally aren't prescribed unless you've tried other antidepressants first without improvement. Randomised controlled study of sleep after nefazodone or paroxetine treatment in out-patients with depression. Side effects of antidepressants vary from one medication to another and from person to person. No changes in psychomotor performance were seen. Avoid alcohol and recreational drugs.
One participant dropped out due to adverse side effects. If your medication doesn't seem to be working or is causing bothersome side effects, call your doctor before making any changes. Talk with your doctor or therapist if you need help with alcohol or drug problems.
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